11 Best Supplements for Hasimoto’s Disease

Last Updated on August 10, 2026 by Carrie Korem, FNTP

Using whole food thyroid supplements to support your thyroid and immune system system can be very helpful when you have Hashimoto’s disease. I used whole food supplements to help reverse my Hashimoto’s and have seen specific supplements be an amazing support for my clients with thyroid autoimmunity. Here are the best supplements for Hashimoto’s that have the most benefit. 

What is Hashimoto’s disease?

Hashimoto’s is an autoimmune condition where your immune system attacks your thyroid tissues.

It’s important to understand that Hashimoto’s is an immune system issue that can affect the thyroid. But, it’s not inherently a thyroid issue. 

How can supplements help Hashimoto’s?

Whole food supplements can help nourish the tissues of the body at the cellular level to bring health and balance back to the organs and systems of the body. 

It’s good to remember that they are a tool to be used alongside a nutrient-dense diet, sleep, detox, and stress reduction. When you use them in this way, you can see the most benefit.

What supplements should people with Hashimoto’s avoid? 

There isn’t a specific list of supplements that everyone with Hashimoto’s should avoid. We are all biochemically individual, so what works well for one person, might not for another.

It’s always best to talk to your practitioner about the right supplements for your situation. This will save you so much time, energy and money in the long run!

Here are the 11 Best Supplements for Hashimoto’s

1. Thytrophin PMG – This supplement supports the thyroid at the cellular level and is incredibly helpful for Hashimoto’s. It is a unique profile of minerals, nucleotides, and peptides that support the tissues.

It doesn’t contain any T4, so you can take this without it elevating your thyroid hormones. 

2. Cataplex E – If you’re looking for a good selenium and vitamin E supplement, this is a great choice. 

Selenium is important for the conversion of FT4 to FT3 in the liver. It also helps to support the thyroid in making thyroid hormones. 

Studies have also shown that selenium can help reduce TPO antibodies and support the immune system. Vitamin E is an antioxidant that is helpful to support proper thyroid function.

Cataplex E also supports cell signaling and regulation of gene expression.

3. Zypan – Most people with Hashimoto’s have low stomach acid which then leads to things such as: nutrient deficiencies, leaky gut, heartburn, constipation, loose stools, etc. 

When the stomach doesn’t produce enough stomach acid, your body cannot use the nutrients in your food. So, proper stomach acid production is crucial to heal the immune system and reduce antibodies.

Zypan is a combination of hydrochloric acid and digestive enzymes and is a wonderful way to support over all gut health and being to replenish nutrient deficiencies. 

4. Ashwaghanda Forte – This is an herbal supplement that can be a rejuvenating tonic for stress, the immune system, and cognition support.*

Ashwaghanda Forte supports:
The body’s natural immune system
General well-being after challenges and stress
Healthy cognition, learning, and memory
The nervous system

*Some who have autoimmunity don’t do well on adaptogenic herbs, so again, always talk to your practitioner about what’s best for you.

5. Drenamin – While this is known as an adrenal supplement, the health and balance of the adrenals and HPA-axis plays a big part in thyroid balance and the health of the immune system. Drenamin can be a fantastic way to support both the adrenals and thyroid.

How Drenamin helps the body:

• Supports adrenal function
• Maintains emotional balance
• Encourages a healthy response to everyday environmental stresses and supports immune system response function
• Maintains energy production
• Supports a balanced mood
• Excellent source of riboflavin and niacin
• Good source of vitamin B6 and antioxidant vitamin C

6. Cod Liver Oil – is a great source of vitamins A, D and omega-3 fatty acids.

Vitamin A is a very important fat-soluble vitamin for the thyroid and immune system. It helps balance the correct levels of thyroid hormones in the body, and is also needed for proper liver function (which plays a part in thyroid hormone balance).

Vitamin D is necessary for iodine to be used to create thyroid hormones. Without adequate vitamin D, you will often see a decrease in FT4 and/or FT3, leading to hypothyroidism. 

Several clinical studies have reported low vitamin D in those with Hashimoto’s, indicating an association between vitamin D deficiency and thyroid autoimmunity.

Impaired vitamin D signaling has been reported to encourage thyroid tumorigenesis.

Vitamin D deficiency has been strongly associated with higher TSH levels (aka hypothyroidism).

Vitamin D regulates insulin and balances blood sugar. When blood sugar is imbalanced, this can cause thyroid hormones to go off balance.

My two favorite brands of cod liver oil are:
Standard Process cod liver oil 
Green Pastures fermented cod liver oil (use the code ORGANIC10 to save 10%)

7. Cataplex B – B vitamins such as Thiamin, Riboflavin, and B12 help support the entire endocrine system. B6 and B12 are especially calming for the nervous system, which helps support the adrenals and, in turn, the thyroid and immune system. B vitamins also work with iodine to produce T4 and T3.

Cataplex B is my go-to and is an excellent source of thiamin, niacin, and vitamin B6.

Cataplex B supports:
A healthy heart
The central/peripheral nervous systems
Energy production in all cells
Healthy cholesterol levels already within a normal range
Healthy homocysteine levels

8. Zinc – Zinc is needed for TSH production and for the conversion of FT4 to FT3. It’s also needed to create proper amounts of stomach acid, which enables the body to utilize the nutrients in your food.

Zinc Chelate is a good choice for short-term zinc supplementation. Remember, zinc and stomach acid work synergistically together, so if you find you’re continually deficient in zinc, ensure your body is making enough stomach acid.

9. Magnesium – This is an essential mineral for thyroid function and for the conversion of T4 to T3. Studies have shown that low magnesium is associated with a higher risk of increased TgAB, and increases the prevalence of Hashimoto’s.

E-Z Mg is an organic, plant-based magnesium and is ideal because it contains a collection of various forms of magnesium. This helps take the guesswork out of which kind of magnesium to take! 

10. Betafood – The health of the liver is very important so the body can convert FT4 to FT3. Betafood is a great supplement to help support the liver’s natural detoxification process to maintain healthy FT3 levels.

11. Catalyn GF – This is my favorite whole food multivitamin. When one has Hashimoto’s, there are often many nutrient deficiencies, so a good multi can help cover what you’re not getting in your diet and also replenish.

How Catalyn supports the body: 

• Contains 12 whole food ingredients including whole food concentrates from the Standard Process Organic Farm.
• Provides multiple vitamin catalysts for overall well-being and energy metabolism.

How can I learn more about the steps I can take for Hashimoto’s?

I have four fantastic options for you!